Spike Blops are Spiny-like organisms located in Bowser's body in Mario & Luigi: Bowser's Inside Story & Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey. In this game, they are located in the Trash Pit and Pump Works just like the Goombule.
Spike Blops can only be defeated by special attacks or a hammer. If they are jumped on, Mario and/or Luigi lose a single point of HP, meaning that the two special attacks; Spin Pipe and Magic Window don't effect them, due to those attacks involving jumping instead, result in injury.
They attack either by squirming into the bros. or by sticking onto walls onto the top and then falling on top of a bro. Their shadow casting above a bro. indicates which one they attack once they squirm on the top of the wall. When they attack, they must be countered by hammers.