Megavitamins are items that Dr. Mario use to kill Viruses. They come in red, blue, or yellow. Mario invented Megavitamins in order to combat the viruses that plague the world. First appearing in Dr. Mario in 1990.
Megavitamins also appear in Super Smash Bros. Melee as Dr. Mario's "B" move.
Tetris and Dr. Mario (1994)
Dr. Mario 64 (2001)
Nintendo Puzzle Collection (2003)
Dr. Mario and Puzzle League (2005)
Dr. Mario Online Rx (2008)
Dr. Mario Express (2008)
Dr. Luigi (2013)
Dr. Mario: Miracle Cure (2015)
Dr. Mario World (2019)