In Super Mario Odyssey, Bowser hires them to plan his wedding to Princess Peach. However, Mario then tries to stop them, battling them throughout the game's many kingdoms. When he reaches Bowser's Kingdom, they attack him in a giant robot called RoboBrood. However, Mario defeats their machine, causing it to launch into the sky and explode with them still inside. Once Mario has successfully stopped the wedding, the four smaller members, now jobless, head off Mario within the carrot-shaped Rabbit Ridge Tower on the Dark Side for a final confrontation. From there, they challenge Mario to a fight against each, back-to-back, for the Multi Moon, culminating in another battle against the RoboBrood. Once RoboBrood is defeated again, it once again launches off and explodes, leaving the Broodals' ultimate fate unknown.
- Madame Broode (Leader)
- Topper (Client Relations)
- Hariet (Pyrotechnics)
- Spewart (Entertainer)
- Rango (Bouncer)
- Chain Chompikins (Pet)
- The Broodals' connection with the Moon seems to be based on the mythological moon rabbit, a creature based on the Moon's markings vaguely resembling a rabbit with a mortar and pestle.
- The name "Broodal" seems to be a combination of "brood," which can refer to either a family of young animals or to dwell unhappily on something, "bridal," referring to their job as wedding planners, and perhaps "brutal,” referring to them being villains.
- The Broodals sometimes make sounds similar to those made by Star Bunnies.
- When the Broodals go into their hats, they resemble flying saucers. Given their lunar origin, this is probably intentional, especially due to the presence of Yoofoes and Torkdrift, which are flying saucers themselves.
- Their battle theme shares similarities to King Kaliente's theme in Super Mario Galaxy.
- The way they go into and out of their hats may reference the common magician's trick of pulling a rabbit out of a hat.
- With the exception of Madame Broode, they are the only bosses in Super Mario Odyssey that can be stomped on.