Like a normal 1-Up item, 1-Up Supers revive a fallen Bro, but instead, it restores the HP meter to full instead of half. They are generally more expensive and rarer to find in blocks than normal 1-Ups.
In the first two Mario & Luigi games, they are known as 1-Up Supers, but in Mario & Luigi: Bowser's Inside Story, they were renamed to 1-Up Deluxes. They have maintained that name in Mario & Luigi: Dream Team and Mario & Luigi: Paper Jam. In Paper Jam, they are referred to as 1-Up DX. In Mario & Luigi: Superstar Saga + Bowser's Minions, they are once again called 1-Up Supers.
Mario and Luigi: Superstar Saga
|Mario & Luigi: Superstar Saga||Item||2003||GBA|
|Mario & Luigi: Partners In Time||Item||2005||DS|
|Mario & Luigi: Bowser's Inside Story||Item||2009||DS|
|Mario & Luigi: Dream Team||Item||2013||3DS|
|Mario & Luigi: Paper Jam||Item||2015||3DS|
|Mario & Luigi: Superstar Saga + Bowser's Minions||Item||2017||3DS|
|Mario & Luigi: Bowser's Inside Story + Bowser Jr.'s Journey||Item||2019||3DS|